Results 261 to 270 of about 19,419,888 (317)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Data-Driven Engineering of Thermostable Collagen-Mimetic Peptoid Triple Helices. [PDF]

Macromol Rapid Commun
Berlaga A, Zheng R, Zhang Z, Lee J, Gandhi D, Chen CL, Ferguson AL.   +6 more
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Synthesis and machine learning techniques to enable data-driven investigation of supramolecular host-guest interactions. [PDF]

Chem Sci
Shaurya A, Bagherzadeh Mostaghimi AH, Turnbull DR, Hof F, Van Humbeck JF.   +4 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Data-driven hypothesis discovery from disease trajectories in multiple sclerosis. [PDF]

Front Immunol
Jodts N, Werthen-Brabants L, Aerts S, Peeters LM, Van Wijmeersch B, Herzeel C, Meertens C, Wuyts R, Dhaene T, Deschrijver D.   +9 more
europepmc   +1 more source

Data-driven subtyping and staging of ALS: A multicenter, longitudinal, deformation-based morphometry study. [PDF]

Imaging Neurosci (Camb)
Lajoie I, Kalra S, Dadar M.
europepmc   +1 more source

Decoding extremophiles: insights from bioinformatics, machine learning, and data-driven approaches. [PDF]

Brief Bioinform
Chasapi MN, Kontis N, Lehmann R, Tasneem R, Patel NS, Khan SA, Martínez de Morentin X, Chasapi IN, Aplakidou E, Galaras A, Aldakheel L, Su M, Baltoumas FA, Venkateswaran K, Lagani V, Gómez-Cabrero D, Tegnér J, Pavlopoulos GA, Soares Rosado A.   +18 more
europepmc   +1 more source

Data-driven insights into the performance of scalable magnetic clay-based composites for pollutant removal. [PDF]

RSC Adv
Vespignani M, Ortelli S, Blosi M, Zanoni I, Takhsha M, Albertini F, Furxhi I, Naldi M, Mensah W, Piraccini A, Costa AL.   +10 more
europepmc   +1 more source