Results 151 to 160 of about 31,155,536 (302)

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai   +13 more
wiley   +1 more source

Data-driven policy learning for continuous treatments

open access: yesJournal of Econometrics
This paper studies policy learning for continuous treatments from observational data. Continuous treatments present more significant challenges than discrete ones because population welfare may need nonparametric estimation, and policy space may be infinite-dimensional and may satisfy shape restrictions.
Chunrong Ai, Yue Fang, Haitian Xie
openaire   +2 more sources

Machine learning-driven data integration for drug discovery

open access: yes
MACHINE LEARNING-DRIVEN DATA INTEGRATION FOR DRUG DISCOVERY Machine learning-driven data integration for drug discovery / Mejia Morelli, Flavio (Rights reserved) (-
Mejia Morelli, Flavio
core  

Early Clinical and Cerebrospinal Fluid Predictors of 1‐Year Recurrence in Autoimmune GFAP Astrocytopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong   +10 more
wiley   +1 more source

Anticoagulation Treatment Response Among Phenotypic ESUS Clusters: Evidence From CASPR

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate treatment effect heterogeneity across phenotypic clusters of patients with cryptogenic embolic stroke using causal inference methods. Methods From a retrospective, multicenter cohort of patients with cryptogenic embolic stroke, we estimated the treatment effect of anticoagulation versus antiplatelet therapy in patients ...
Elena Badillo Goicoechea   +53 more
wiley   +1 more source

Do-it-yourself corpora for LSP: Demystifying the process and illustrating the practice

open access: yesScripta Manent, 2019
This paper argues for an approach to LSP in which teachers and students compile their own do-it-yourself corpora using specialised texts in their area of study and teaching. I show that it is relatively easy to build a rough and ready corpus of this type
Maggie Charles
doaj  

Sparse Data-Driven Learning for Effective and Efficient Biomedical Image Segmentation. [PDF]

open access: yesAnnu Rev Biomed Eng, 2020
Onofrey JA   +7 more
europepmc   +1 more source

The Role of Machine Learning in Entrepreneurial and Investment: A Systematic Literature Review on Data Driven Decision Making

open access: yes
The Role of Machine Learning in Entrepreneurial and Investment: A Systematic Literature Review on Data Driven Decision Making ...
Murniati, Murniati
core   +1 more source

Learning to select software components [PDF]

open access: yes, 2004
Developers using software components need to be confident in their selection of the most suitable component. Manual searching is time consuming and unlikely to be able to consider large numbers of components. The Context-driven Component Evaluation (CdCE)
Maxville, V., Lam, C.P., Armarego, J.
core  

Dysregulated Cholesterol Metabolism, Chronic Inflammation, and Disability in Severe Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Dysregulated lipid metabolism, which can affect remyelination and neural repair, has not been extensively investigated in progressive multiple sclerosis (PMS). The goal was to examine whether dysregulated cholesterol metabolism was associated with disability in PMS. Methods The study sample comprised 53 Severe PMS patients (Expanded
Taylor R. Wicks   +8 more
wiley   +1 more source

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