Results 141 to 150 of about 29,019,899 (298)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Example of Synthesized Data Experiment
An experiment of comparing methods on synthesized data set, with detail data and estimation ...
Chen, Zirui +3 more
core +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Overview: The Integrated Multimedia City Household Survey dataset was produced as a result of a collaborative Economic and Social Research Council, ESRC-funded project across the University of Glasgow, Newcastle and Sheffield.
Lido, Catherine +1 more
core
Raw data of the BabyGlucoLight project
Data collected during the BabyGlucoLight clinical trial. It contains raw glucose data measured with continuous glucose monitoring during the first days of life in very preterm newborns as well as their simultaneous measured raw brain hemodynamic data ...
Brigadoi, Sabrina +8 more
core +1 more source