Results 151 to 160 of about 37,394,520 (286)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Characteristics and Outcomes After General Anaesthesia in Elderly Patients: A Nationwide Cohort Study. [PDF]

Acta Anaesthesiol Scand
Risager BH, Mortensen SØ, Pælestik MB, Stankovic N, Lind PC, Andersen LW.   +5 more
europepmc   +1 more source

Data, data, data…

International Journal of Clinical Practice, 2007
openaire   +1 more source

Good data, bad data and ugly data [PDF]

Nature Microbiology, 2019
openaire   +2 more sources

RV Investigator Voyage IN2024_V02 ADCP Data

Maintenance and Update Frequency: asNeededStatement: Original field data. Data processing and quality control: Performed by the NCMI DAP Group. Note that 1min average data is provided as a special request, however it is unedited and has data quality ...

core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Effects of Participation in a Community-Based Food Cooperative on Food Security and Dietary Behaviours: A Pre-Post Study. [PDF]

Health Promot J Austr
Hliounakis H, Kent K, Brooks C, Scavera J, Fleming C, Morrison N, Si L, Simmons D, Wu JHY, Chapman L, MacMillan F.   +10 more
europepmc   +1 more source

RV Investigator voyages BGC Argo Float Data

Maintenance and Update Frequency: notPlanned<b>Credit</b><br/>These data were collected on the Marine National Facility (MNF) RV Investigator voyages.

core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source