Results 261 to 270 of about 63,638,251 (398)

Grand challenges in mathematical biology: Integrating multi-scale modeling and data

open access: yesFrontiers in Applied Mathematics and Statistics, 2022
Raluca Eftimie
doaj   +1 more source

Adaptations and Heterogeneity of Treatment Effects in Platform Trials-Protocol for Two Methodological Studies. [PDF]

open access: yesActa Anaesthesiol Scand
Meyhoff TS   +6 more
europepmc   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

open access: yesMolecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song   +13 more
wiley   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

A systematic methodological evaluation of sepsis guidelines: Protocol for quality assessment and consistency of recommendations. [PDF]

open access: yesActa Anaesthesiol Scand
Amer M   +22 more
europepmc   +1 more source

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