Results 71 to 80 of about 5,099,006 (286)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Aircraft data acquisition [PDF]

The corn blight project was different than previously planned missions in duration, coverage, and sensor configuration. The wide aerial coverage and single sensor configuration provided flexibility in mission operations that contributed to mission ...
Blilie, R. K.
core   +1 more source

Data management for earth observations [PDF]

, 1977
The management of NASA earth observation data is discussed. User requirements are identified, as well as means to facilitate data acquisition. It is shown that LANDSAT data can be preprocessed to condense data into a more accessible format, thus reducing
Mcdonough, G. F.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

New data acquisition system records bearing measurements directly [PDF]

, 1970
Digital data acquisition system records steady state and dynamic data of bearing and shaft displacement. Elliptical orbits formed can be reconstructed and the data reduced automatically. System also reads pressures, temperatures, flows, and torque during
Rossbach, R. J.
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Doppler-enhanced FMCW LiDAR odometry based on linear continuous-time representation [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
LiDAR-based simultaneous localization and mapping (SLAM) plays a crucial role in applications such as search and rescue, infrastructure inspection, and underground exploration. However, conventional LiDAR-based methods often exhibit significantly reduced
W. Wu, C. Chen, C. Chen, C. Chen, B. Yang, B. Yang, B. Yang, Y. Xu, Y. Xu, Y. Xu, Y. Shen, X. He   +11 more
doaj   +1 more source

On-the-fly Data Assessment for High Throughput X-ray Diffraction Measurement

, 2017
Investment in brighter sources and larger and faster detectors has accelerated the speed of data acquisition at national user facilities. The accelerated data acquisition offers many opportunities for discovery of new materials, but it also presents a ...
Hexemer, Alexander, Mehta, Apurva, Pandolfi, Ronald, Ren, Fang, Van Campen, Douglas   +4 more
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source