Results 81 to 90 of about 26,684,243 (354)

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

Standards and Protocols for Data Acquisition and Reporting for Studies of the Electrochemical Reduction of Carbon Dioxide

ACS Catalysis, 2018
Objective evaluation of the performance of electrocatalysts for CO2 reduction has been complicated by a lack of standardized methods for measuring and reporting activity data. In this perspective, we advocate that standardizing these practices can aid in
E. Clark, Joaquin Resasco, A. Landers, John C. Lin, L. Chung, Amber Walton, C. Hahn, T. Jaramillo, A. Bell   +8 more
semanticscholar   +2 more sources

Advanced Data Acquisition From Electron Microscopes With SerialEM

Microscopy and Microanalysis, 2018
The SerialEM package provides a comprehensive interface for microscope control, image acquisition and display, and automated data acquisition of various kinds 1 .
D. Mastronarde
semanticscholar   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

FEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset   +9 more
wiley   +1 more source

Remote controlled partial discharge acquisition unit [PDF]

, 2003
Online partial discharge (PD) analysis for underground high voltage cables has major advantages over the offline techniques. Online techniques usually involve PD data acquisition, storage and post-processing of the data.
Foo, M.H., Pearson, J.S., Siew, W.H., Soraghan, J.J.   +3 more
core  

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Programmable parametric filter with noise generator and data acquisition [PDF]

, 2019
Audio filtering systems are used in commercial applications involving equalizers. However, some of the topologies used can be modified to be used in audio signal treatment applications.
Martínez García, Herminio
core  

Data acquisition system for the MuLan muon lifetime experiment

, 2008
We describe the data acquisition system for the MuLan muon lifetime experiment at Paul Scherrer Institute. The system was designed to record muon decays at rates up to 1 MHz and acquire data at rates up to 60 MB/sec.
Barnes, Brun, Chitwood, D.B. Chitwood, D.M. Webber, F. Gray, Frlez, Huffman, I. Logashenko, K.R. Lynch, S. Battu, S. Cheekatmalla, S. Dhamija, S. Rath, T.P. Gorringe, V. Tishchenko   +15 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source