Results 111 to 120 of about 1,447,119 (292)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Efficient unpaired data validation and aggregation protocol in industrial Internet of things
Tongxin xuebaoAs a cornerstone technology of smart manufacturing, the industrial Internet of things (IIoT) harnesses efficient data sharing to propel the networking, digitization, and intellectualization of industrial production, thereby assisting manufacturing ...
MA Rong, FENG Tao
doaj
Combining Objects with Rules to Represent Aggregation Knowledge in Data Warehouse and OLAP Systems [PDF]
Data warehouses are based on multidimensional modeling. Using On-Line Analytical Processing (OLAP) tools, decision makers navigate through and analyze multidimensional data.
Akoka, Jacky +2 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
TESTING FOR AGGREGATION AND SIMULTANEOUS BIAS IN U.S. SOYBEAN EXPORT EQUATIONS [PDF]
Most previous estimates of elasticities of export demand for U.S. soybeans have emanated from single import equations subject to aggregation and simultaneous equation bias. This analysis tests U.S.
Arnade, Carlos A., Davison, Cecil W.
core +1 more source
Consensus-based clustering and data aggregation in decentralized network of multi-agent systems. [PDF]
PeerJ Comput Sci, 2023 Damanik JJ +4 more
europepmc +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Remote SensingLand cover products are essential tools in environmental and ecological research. However, limited attention has been paid to their data quality issues.
Jinghan Wang +5 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source