Results 111 to 120 of about 50,356,783 (293)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng +3 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida +11 more
wiley +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
, 2015 The open data impact map is a searchable, centralized database of open data use cases from around the world. It is a collaborative effort that draws on previous studies, examples from an international network of Regional Supporters, an online survey ...
Center for Open Data Enterprise
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
BMC GastroenterologyIntroduction Inflammatory bowel diseases (IBD), mainly represented by Crohn’s disease and ulcerative colitis, have a multifactorial etiology and a growing incidence in developing countries.
Jenny Diniz Malentaqui Lousada +6 more
doaj +1 more source
Advances in Data Analysis and Classification
, 2013 The international journal Advances in Data Analysis and Classification (ADAC) is designed as a forum for high standard publications on research and applications concerning the extraction of knowable aspects from many types of data.
MONTANARI, ANGELA
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
A comparison of embedding aggregation strategies in drug–target interaction prediction
BMC BioinformaticsThe prediction of interactions between novel drugs and biological targets is a vital step in the early stage of the drug discovery pipeline. Many deep learning approaches have been proposed over the last decade, with a substantial fraction of them ...
Dimitrios Iliadis +3 more
doaj +1 more source
An antimicrobial drug recommender system using MALDI-TOF MS and dual-branch neural networks
eLifeTimely and effective use of antimicrobial drugs can improve patient outcomes, as well as help safeguard against resistance development. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is currently routinely ...
Gaetan De Waele +2 more
doaj +1 more source