Results 251 to 260 of about 14,606,600 (299)

A dual approach to evaluate the performance of RNA-Seq data analysis pipelines with weak signals. [PDF]

Bioinform Adv
Baroudi M, Ly FO, Goujon E, Ibanez C, Macé L, Zouali H, Armant O, Grison S, Benadjaoud M, Garali I.   +9 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Unraveling genotype-phenotype relationships in hereditary hemochromatosis through integrated biobank data analysis. [PDF]

BMC Genomics
Nurm M, Annilo T, May-Wilson S, Reigo A, Mägi R, Võsa U, Tõnisson N, Estonian Biobank Research Team, Haller T.   +8 more
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Long-term trends in metabolic profiles across Chinese birth cohorts: A real-world big data analysis. [PDF]

Clin Transl Med
Xiong Y, Duan X, Zhu J, Huang J, Pan B, Shao W, Wang B, Guo W.   +7 more
europepmc   +1 more source

Biochef: a client-side WebAssembly-based workflow builder for genomic data analysis. [PDF]

BMC Bioinformatics
Rosa J, Andrade J, Silva JM, Oliveira JL.   +3 more
europepmc   +1 more source

Guide to dynamic OCT data analysis. [PDF]

Biomed Opt Express
Heldt N, Monfort T, Morishita R, Schönherr R, Thouvenin O, El-Sadek IA, König P, Hüttmann G, Grieve K, Yasuno Y.   +9 more
europepmc   +1 more source

Connect Kits for Family Action: Intervention Development and Exploratory Data Analysis of Proximal Outcomes. [PDF]

J Child Adolesc Subst Use
Komro KA, Skinner JR, Ivanich E, Barry CM, Jagtiani A, Livingston BJ, Talavera-Brown SL, LaBounty H, Gassaway AN, Livingston MD.   +9 more
europepmc   +1 more source