Results 101 to 110 of about 26,844,009 (300)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono   +7 more
wiley   +1 more source

A Dynamic System to Control the Entry of Non-Authorized Visitors and Detect Superspreader Farms in Strongly Interconnected Systems

open access: yesAnimals
This study explores the critical challenges the livestock sector faces, particularly those related to biosecurity, animal welfare, and antibiotic use restrictions. It highlights the need to implement advanced information and communication technologies to
Oscar Soriano   +4 more
doaj   +1 more source

Generating geologically realistic 3D reservoir facies models using deep learning of sedimentary architecture with generative adversarial networks

open access: yesPetroleum Science, 2019
This paper proposes a novel approach for generating 3-dimensional complex geological facies models based on deep generative models. It can reproduce a wide range of conceptual geological models while possessing the flexibility necessary to honor ...
Tuan-Feng Zhang   +5 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Assessment of Medical Waste Segregation, Disposal Practices for Infectious and Sharps Waste in Healthcare Facilities in Somalia: Implications for Infection Prevention and Control

open access: yesInfection and Drug Resistance
Abdikarim Abdi Adam,1,2 Felix Emeka Anyiam,3 Mukhtar Abdi Shube,2 Hassan Dahir Mohamed,1 Hassan Abdi Ahmed,1 Nor Haji Osman1 1Department of Statistics and Data Analytics, Jamhuriya University of Science and Technology (JUST), Mogadishu, Somalia; 2Public ...
Adam AA   +5 more
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The many revelations of and about inequality data in the context of COVID-19: introducing a special issue on COVID-19 and inequality

open access: yesInternational Journal for Equity in Health, 2023
Ahmad Reza Hosseinpoor   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy