Results 31 to 40 of about 1,249,061 (355)

Organizational Resilience in Data Archives: Three Case Studies in Social Science Data Archives

Data Science Journal, 2017
As public investment in archiving research data grows, there has been increasing attention to the longevity or sustainability of the data repositories that curate such data.
Kristin R. Eschenfelder, Kalpana Shankar
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Five Suggestions Towards User-Centred Data Repositories in the Social Sciences

Data Science Journal
Data repositories for the social sciences are facing some discipline-specific challenges. This essay provides an overview of the four key challenges. In addition, five suggestions are made to strengthen domain-specific online data repositories in the ...
Elias Herman Kruithof, Christophe Vanroelen, Laura Van den Borre   +2 more
doaj   +1 more source

A Network of Knowledge: A New Model for Collaborative Digital Reference Services in Iran's Top Universities [PDF]

نشریه مطالعات دانش‌پژوهی
Purpose: The study aims to develop a model for collaborative digital reference services among central libraries in Iran’s leading universities. This model seeks to improve access to information, enhance user collaboration, and promote knowledge sharing ...
Azam Najafgholinejad, Sahar Sabeghi
doaj   +1 more source

Agile development of the SSH Open Marketplace: User Workshop [PDF]

ITM Web of Conferences, 2020
For the release of the Alpha version of the SSH Marketplace, we arranged a two-hour slot on 30 June 2020 during the ICTeSSH 2020 Conference. This report provides the context for the development of the Marketplace and presents the feedback received from ...
Barbot Laure, Biller Tracey, Broeder Daan, Dekker Ron, Durco Matej, Vipavc Irene, Willems Marieke   +6 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Data Archives Retrospective and Perspective

IASSIST Quarterly, 1980
Data Archives Retrospective and ...
N. K. Nijhawan
doaj   +1 more source

Archiving raw crystallographic data [PDF]

Acta Crystallographica Section D Biological Crystallography, 2014
This article describes some of the activities of the IUCr Diffraction Data Deposition Working Group and introduces a collection of articles discussing the archiving of diffraction images.
openaire   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

The Role of the Researcher in the Qualitative Research Process. A Potential Barrier to Archiving Qualitative Data

Forum: Qualitative Social Research, 2000
The Danish Data Archives (the DDA) is as other data archives about to take up the challenge of archiving and disseminating qualitative research material in addition to quantitative material.
Anne Sofia Fink
doaj