Results 41 to 50 of about 1,247,210 (302)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Transformative Effects of NDIIPP, the Case of the Henry A. Murray Archive [PDF]

, 2009
This article comprises reflections on the changes to the Henry A. Murray Research Archive, catalyzed by involvement with the National Digital Information Infrastructure and Preservation Program (NDIIPP) partnership, and the accompanying introduction ...
Altman, Micah
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

The Role of the Researcher in the Qualitative Research Process. A Potential Barrier to Archiving Qualitative Data

Forum: Qualitative Social Research, 2000
The Danish Data Archives (the DDA) is as other data archives about to take up the challenge of archiving and disseminating qualitative research material in addition to quantitative material.
Anne Sofia Fink
doaj  

Data Archives Retrospective and Perspective

IASSIST Quarterly, 1980
Data Archives Retrospective and ...
N. K. Nijhawan
doaj   +1 more source

Searching Heterogeneous Human Digital Memory Archives [PDF]

, 2007
Advances in digital storage technologies mean that vast digital archives of ones personal life experiences can now be generated. These personal archives (Human Digital Memories (HDMs)) can contain many types of data in various media created or accessed ...
Kelly, Liadh
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Data on the Margins – Data from LGBTIQ+ Populations in European Social Science Data Archives

Data Science Journal
Data gaps are a significant lack of data about marginalized groups existing due to unequal power relations (D’Ignazio and Klein, 2020). They both perpetuate and result in a dominance of male, white, hetero, and cis perspectives in how we make sense of ...
Jonas Recker, Anja Perry
doaj   +1 more source

Estonian Social Science Data Archives

IASSIST Quarterly, 2001
Estonian Social Science Data ...
Rein Murakas, Andu Rämmer
doaj   +1 more source

Stewardship of very large digital data archives [PDF]

This paper addresses the problems foreseen by the author in stewarding the very large digital data archives that will accumulate during the mission of the Earth Orbiting Satellite (EOS).
Savage, Patric
core   +4 more sources