Results 31 to 40 of about 1,247,210 (302)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Ocean Data: Collectors to Archives [PDF]

open access: yesProceedings of OceanObs'09: Sustained Ocean Observations and Information for Society, 2010
Preserving data for future use involves the acquisition, processing, preservation, quality assurance or control (QC) or assurance, archival preservation (including accompanying platform and instrumental metadata), and dissemination by data centres serving national and international users [1].
Keeley, Robert   +4 more
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Five Suggestions Towards User-Centred Data Repositories in the Social Sciences

open access: yesData Science Journal
Data repositories for the social sciences are facing some discipline-specific challenges. This essay provides an overview of the four key challenges. In addition, five suggestions are made to strengthen domain-specific online data repositories in the ...
Elias Herman Kruithof   +2 more
doaj   +1 more source

Organizational Resilience in Data Archives: Three Case Studies in Social Science Data Archives

open access: yesData Science Journal, 2017
As public investment in archiving research data grows, there has been increasing attention to the longevity or sustainability of the data repositories that curate such data.
Kristin R. Eschenfelder, Kalpana Shankar
doaj   +1 more source

Data-Driven Reporting and Processing of Digital Archives with Brunnhilde [PDF]

open access: yes, 2017
[Excerpt] Archivists are now several decades in to appraising, arranging, describing, preserving, and providing access to digital archives and have developed and adopted a number of tools to aid in specific tasks along the way.
Walsh, Tim
core   +1 more source

Legal Deposit Web Archives and the Digital Humanities: a Universe of Lost Opportunity? [PDF]

open access: yes, 2018
Legal deposit libraries have archived the web for over a decade. Several nations, supported by legal deposit regu-lations, have introduced comprehensive national domain web crawling, an essential part of the national library re-mit to collect, preserve ...
Berube, Linda   +2 more
core   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

A Network of Knowledge: A New Model for Collaborative Digital Reference Services in Iran's Top Universities [PDF]

open access: yesنشریه مطالعات دانش‌پژوهی
Purpose: The study aims to develop a model for collaborative digital reference services among central libraries in Iran’s leading universities. This model seeks to improve access to information, enhance user collaboration, and promote knowledge sharing ...
Azam Najafgholinejad, Sahar Sabeghi
doaj   +1 more source

Small Data Archives and Libraries [PDF]

open access: yes, 2010
Preservation is important for documenting original observations, and existing data are an important resource which can be re-used. Observatories should set up electronic data archives and formulate archiving policies.
Holl, András
core  

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