Results 41 to 50 of about 25,318,700 (300)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Strengthening institutional data management and promoting data sharing in the social and economic sciences

Liber Quarterly: The Journal of European Research Libraries, 2017
In the German social and economic sciences there is a growing awareness of flexible data distribution and research data reuse, especially as increasing numbers of research funders recommend publishing research data as the basis for scientific insight ...
Monika Linne, Wolfgang Zenk-Möltgen
doaj   +1 more source

Preparing a Data Archive or Repository for Changing Research Data and Materials Retention Policies

Journal of eScience Librarianship, 2021
Archival expectations and requirements for researchers’ data and code are changing rapidly, both among publishers and institutions, in response to what has been referred to as a “reproducibility crisis.” In an effort to address this crisis, a number of ...
Jonathan Bohan, Lynda Kellam
doaj   +1 more source

The SUMER Data in the SOHO Archive [PDF]

Solar Physics, 2013
38 pages, 9 figures, accepted for publication by Solar ...
Germerott, Dietmar, Schühle, Udo, Curdt, Werner, Teriaca, Luca, Wilhelm, Klaus, Lemaire, Philippe, Bocchialini, Karine, Innes, Davina   +7 more
openaire   +3 more sources

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Giant Planet Observations in NASA’s Planetary Data System

Remote Sensing, 2022
While there have been far fewer missions to the outer Solar System than to the inner Solar System, spacecraft destined for the giant planets have conducted a wide range of fundamental investigations, returning data that continues to reshape our ...
Nancy J. Chanover, James M. Bauer, John J. Blalock, Mitchell K. Gordon, Lyle F. Huber, Mia J. T. Mace, Lynn D. V. Neakrase, Matthew S. Tiscareno, Raymond J. Walker   +8 more
doaj   +1 more source

Ocean Data: Collectors to Archives [PDF]

Proceedings of OceanObs'09: Sustained Ocean Observations and Information for Society, 2010
Preserving data for future use involves the acquisition, processing, preservation, quality assurance or control (QC) or assurance, archival preservation (including accompanying platform and instrumental metadata), and dissemination by data centres serving national and international users [1].
Keeley, Robert, Woodruff, S, Pouliquen, Sylvie, Conkright-gregg, M, Reed, G   +4 more
openaire   +2 more sources

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source