Results 81 to 90 of about 25,318,700 (300)
Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity
Advanced Science, EarlyView.This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj +25 more
wiley +1 more source
대한영상의학회지, 2017 This special report aimed to document our experiences in implementing the Central Imaging Archiving and Management System (CIAMS) for a multicenter clinical trial, Low-dose CT for Appendicitis Trial (LOCAT), supported by the Korean Society of Radiology ...
Yousun Ko +8 more
doaj +1 more source
IUCrJ, 2017 A topical review is presented of the rapidly developing interest in and storage options for the preservation and reuse of raw data within the scientific domain of the IUCr and its Commissions, each of which operates within a great diversity of ...
Loes M. J. Kroon-Batenburg +3 more
doaj +1 more source
, 2019 Tussen 1997 en 2005 hebben het Nederlands Instituut voor Wetenschappelijke Informatiediensten (NIWI-KNAW), het Centraal Bureau voor de Statistiek (CBS), het Internationaal Instituut voor Sociale Geschiedenis (IISG) en de Stichting Historische Databank ...
Doorn, Dr. P.K. (Data Archiving and Networked Services (DANS)) DAI=info:eu-repo/dai/nl/069708959, Editor
core +1 more source
Advanced Science, EarlyView.Using single‐cell transcriptomic and epigenomic profiling, researchers mapped microglial dysfunction across the lifespan of db/db mice. The authors uncovered a nonlinear microglial remodeling featuring early inflammatory priming, a mid‐stage transcriptional inflection, and late dysfunction.
Jizhou Zhang +6 more
wiley +1 more source
Archiving raw crystallographic data [PDF]
Acta Crystallographica Section D Biological Crystallography, 2014 This article describes some of the activities of the IUCr Diffraction Data Deposition Working Group and introduces a collection of articles discussing the archiving of diffraction images.
openaire +2 more sources
Advanced Science, EarlyView.Autonomous laboratories can now synthesize materials faster than experts can interpret the resulting diffraction data. A probabilistic framework combines refinement‐fit metrics with large language model‐derived chemical reasoning to rank competing phase interpretations and flag those unsuitable for autonomous use.
Olympia Dartsi +7 more
wiley +1 more source
Open access self-archiving: An Introduction
, 2005 This, our second author international, cross-disciplinary study on open access had 1296 respondents. Its focus was on self-archiving. Almost half (49%) of the respondent population have self-archived at least one article during the last three years.
Swan, Alma
core +1 more source
Open access self-archiving: An author study
, 2005 This, our second author international, cross-disciplinary study on open access had 1296 respondents. Its focus was on self-archiving. Almost half (49%) of the respondent population have self-archived at least one article during the last three years.
Brown, Sheridan, Swan, Alma
core +1 more source
Giving structure to the "everything else" box: Creating curation standards for qualitative data
IASSIST QuarterlyTo produce high-quality data for future use, Curators must be both proactive in setting FAIR (Findability, Accessibility, Interoperability, and Reuse) standards and flexible in allowing curation standards to evolve alongside methodological and ...
Amanda Draft +5 more
doaj +1 more source