Comparing data assimilation and likelihood-based inference on latent state estimation in agent-based models. [PDF]
Kolic B +3 more
europepmc +1 more source
Model‐Enabled Knowledge Transfer Across Cell Lines, Culture Scales and Conditions
ABSTRACT Mechanistic models are central to quantitative understanding and optimization of Chinese hamster ovary (CHO) cell culture processes, but their utility is often restricted by parameter sets calibrated for specific cell lines, scales, or operating conditions.
Luxi Yu +2 more
wiley +1 more source
Efficient sequential Bayesian inference for state-space epidemic models using ensemble data assimilation. [PDF]
Temfack D, Wyse J.
europepmc +1 more source
A data-assimilation approach to predict population dynamics during epithelial-mesenchymal transition. [PDF]
Mendez MJ +4 more
europepmc +1 more source
ABSTRACT Chinese hamster ovary (CHO) cells are the leading host for recombinant therapeutic protein production in the biopharma industry. In this study, we investigated how feeding acidic forms of tricarboxylic acid (TCA) cycle intermediates—malic acid, succinic acid, and α‐ketoglutaric acid—affects cell culture performance and metabolism in two ...
Sarah A. Sacco +8 more
wiley +1 more source
Data assimilation for estimating time-varying reproduction numbers. [PDF]
Wunrow HY +3 more
europepmc +1 more source
ABSTRACT Synthetic biology has recently proven to be a valuable tool for enhancing agriculture even in the face of environmental and biological stresses. Understanding the challenges that militate synthetic biology will assist in ensuring safe, stable, and scalable crop production.
Ben Jesuorsemwen Enagbonma +6 more
wiley +1 more source
Combining data assimilation of states and parameters for more precise infectious disease prediction. [PDF]
Hao Z +7 more
europepmc +1 more source
Optical Ultrastructure of Cardiac Tissue Helps to Reproduce Discordant Alternans by In Silico Data Assimilation. [PDF]
Hörning M +5 more
europepmc +1 more source
Carrion ecology: concepts, interdisciplinary synthesis, and perspectives
ABSTRACT Carrion is a ubiquitous resource in both terrestrial and aquatic ecosystems, yet it has long been overlooked in ecological research. Over the past two decades, studies on carrion and the many organisms that exploit it have flourished, revealing not only wide‐ranging ecological functions but also significance far beyond ecology.
Marcos Moleón +38 more
wiley +1 more source

