Results 171 to 180 of about 619,416 (280)

Genetically Programmed Control of Overflow Metabolism

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 6, Page 1624-1633, June 2026.
ABSTRACT Overflow metabolism is a highly undesirable phenomenon that occurs in virtually all cell factories. Although several schemes have been applied to avoid overflow metabolism, this problem remains far from being solved. In this study, a genetic sensor for detecting overflow metabolism was designed, and its substrate specificity and reversibility ...
Lærke M. Jensen   +3 more
wiley   +1 more source

Kinetically Consistent Data Assimilation for Plant PET Sparse Time Activity Curve Signals. [PDF]

open access: yesFront Plant Sci, 2022
D'Ascenzo N   +5 more
europepmc   +1 more source

Multi‐Scale Hybrid Modeling to Predict Cell Culture Process With Metabolic Phase Transitions

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT To advance understanding of cellular metabolism and reduce batch‐to‐batch variability in cell culture processes, this study introduces a multi‐scale hybrid modeling framework designed to simulate and predict the dynamic behavior of CHO cell cultures undergoing metabolic phase transitions.
Keqi Wang, Sarah W. Harcum, Wei Xie
wiley   +1 more source

A dataset of winter wheat aboveground biomass in China during 2007-2015 based on data assimilation. [PDF]

open access: yesSci Data, 2022
Huang H   +7 more
europepmc   +1 more source

Thermodynamic Evaluation of Dual Substrate Growth

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Various C₁–C₂ compounds are increasingly available through electrochemical reduction of CO2. Although not always suitable as a sole substrate, these compounds can supplement a primary substrate like glucose to enhance microbial growth. Yet, the mechanisms underlying the effects of dual substrate consumption on growth rate and growth yield ...
Marit A. Verheijen   +3 more
wiley   +1 more source

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