Results 81 to 90 of about 4,379,512 (292)

Review of developments in electronic, clinical data collection and documentation systems over the last decade – Are we ready for Big Data in routine health care?

Frontiers in Oncology, 2016
Recently, information availability has become more elaborate and wide spread, and treatment decisions are based on a multitude of factors including imaging, molecular or pathological markers, surgical results and patient’s preference. In this context the
Kerstin Anne Kessel, Kerstin Anne Kessel, Stephanie E Combs, Stephanie E Combs   +3 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Experiences in running a complex electronic data capture system using mobile phones in a large-scale population trial in southern Nepal

Global Health Action, 2017
The increasing availability and capabilities of mobile phones make them a feasible means of data collection. Electronic Data Capture (EDC) systems have been used widely for public health monitoring and surveillance activities, but documentation of their ...
Sarah Style, B. James Beard, Helen Harris-Fry, Aman Sengupta, Sonali Jha, Bhim P. Shrestha, Anjana Rai, Vikas Paudel, Meelan Thondoo, Anni-Maria Pulkki-Brannstrom, Jolene Skordis-Worrall, Dharma S. Manandhar, Anthony Costello, Naomi M. Saville   +13 more
doaj   +1 more source

Capture and transformation of urban soundscape data for artistic creation

Journal of Science and Technology of the Arts, 2014
URB is a research project designed to collect and store raw data from soundscapes analysis. This paper presents a survey about using URB based on the analysis of work developed by several artists, focusing on the description of their creative process and
José Alberto Gomes, Nuno Peixoto de Pinho, Filipe Lopes, Gustavo Costa, Rui Dias, Diogo Tudela, Álvaro Barbosa   +6 more
doaj   +1 more source

Capturing the Laws of (Data) Nature. [PDF]

, 2015
Model fitting is at the core of many scientific and industrial applications. These models encode a wealth of domain knowledge, something a database decidedly lacks. Except for simple cases, databases could not hope to achieve a deeper understanding of the hidden relationships in the data yet.
Mühleisen, H., Kersten, M., Manegold, S.   +2 more
openaire   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Mapping Current and Potential Sources of Routine Data Capture on New Psychoactive Substances in Scotland [PDF]

, 2015
The paper maps the data currently being captured on NPS, and provides a starting point for exploring the strengths and weaknesses of a number of existing data systems in Scotland, and opportunities for data ...
Gillies, Allan
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source