Results 171 to 180 of about 511,690 (285)

A comparative study of model-centric and data-centric approaches in the development of cardiovascular disease risk prediction models in the UK Biobank. [PDF]

Eur Heart J Digit Health, 2023
Mamouei M, Fisher T, Rao S, Li Y, Salimi-Khorshidi G, Rahimi K.   +5 more
europepmc   +1 more source

Privacy-Centric Data Management

, 2013
This document will focus on my core computer science research since 2010, covering the topic of data management and privacy. More speci cally, I will present the following topics : - A new paradigm, called Trusted Cells for privacy-centric personal data management based on the Asymmetric Architecture composed of trusted or open (low power) distributed ...
openaire   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Enhancing biomedical relation extraction through data-centric and preprocessing-robust ensemble learning approach. [PDF]

Database (Oxford)
Meesawad W, Han JC, Hsueh CY, Zhang Y, Hung HC, Tsai RT.   +5 more
europepmc   +1 more source

What Is a Digital Twin? Experimental Design for a Data-Centric Machine Learning Perspective in Health. [PDF]

Int J Mol Sci, 2022
Emmert-Streib F, Yli-Harja O.
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

A data-centric and interpretable EEG framework for depression severity grading using SHAP-based insights. [PDF]

J Neuroeng Rehabil
Shen A, Sun J, Chen X, Gao X.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Preparing clinical research data for artificial intelligence readiness: insights from the National Institute of Diabetes and Digestive and Kidney Diseases data centric challenge. [PDF]

J Am Med Inform Assoc
Domagalski MJ, Lu Y, Pilozzi A, Williamson A, Chilappagari P, Luker E, Shelley CD, Dabic A, Keller MA, Rodriguez RM, Lawlor S, Thangudu RR.   +11 more
europepmc   +1 more source

A Data-Centric Analysis of the Impact of Non-Electric Data on the Performance of Load Disaggregation Algorithms. [PDF]

Sensors (Basel), 2022
Góis J, Pereira L, Nunes N.
europepmc   +1 more source