Results 61 to 70 of about 340,570 (274)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Joint declaration of data citation principles [PDF]

open access: yes, 2014
Preamble Sound, reproducible scholarship rests upon a foundation of robust, accessible data. For this to be so in practice as well as theory, data must be accorded due importance in the practice of scholarship and in the enduring scholarly record.
Force11
core  

Comparing two "thermometers": Impact factors of 20 leading economic journals according to Journal Citation Reports and Scopus [PDF]

open access: yes, 2009
Impact factors for 20 journals ranked first by Journal Citation Reports (JCR) were compared with the same indicator calculated on the basis of citation data obtained from Scopus database.
Vladimir Pislyakov, Pislyakov, Vladimir
core   +1 more source

Enhanced Publications: Data Models and Information Systems

open access: yesLiber Quarterly: The Journal of European Research Libraries, 2014
“Enhanced publications” are commonly intended as digital publications that consist of a mandatory narrative part (the description of the research conducted) plus related “parts”, such as datasets, other publications, images, tables, workflows, devices ...
Alessia Bardi, Paolo Manghi
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Supporting FAIR data: categorization of research data as a tool in data management

open access: yesInformaatiotutkimus, 2018
The demand for implementation of the FAIR data principles is in many cases difficult for a researcher to adhere to in efficient ways due to lacking tools.
Jessica Parland-von Essen   +4 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

The Oklahoma Mesonet: A Pilot Study of Environmental Sensor Data Citations

open access: yesData Science Journal, 2017
This pilot study of 110 scientific papers utilizing environmental sensor data from the Oklahoma Mesonet during its first two decades of operations demonstrates the diversity of potential purposes in scientific research for a robust, rigorously maintained,
Betsy Van der Veer Martens   +2 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

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