Results 101 to 110 of about 25,970,551 (304)

Improved robustness in time series analysis of gene expression data by polynomial model based clustering [PDF]

open access: yes, 2006
Microarray experiments produce large data sets that often contain noise and considerable missing data. Typical clustering methods such as hierarchical clustering or partitional algorithms can often be adversely affected by such data.
Liu, X   +20 more
core   +1 more source

Data for: Clustering Benchmark Datasets Exploiting the Fundamental Clustering Problems

open access: yes, 2021
This directory contains the Fundamental Clustering Challenges. It contains different data sets with a given classification.The data sets are rather simple and low in dimensionality. Each dataset adresses a certain problem for clustering.
Thrun, M (via Mendeley Data)   +1 more
core   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Consensus clustering and functional interpretation of gene-expression data [PDF]

open access: yes, 2004
Microarray analysis using clustering algorithms can suffer from lack of inter-method consistency in assigning related gene-expression profiles to clusters.
Liu, X   +27 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Robust Adaptive Graph Regularized Non-Negative Matrix Factorization

open access: yesIEEE Access, 2019
Data clustering, which aims to divide the given samples into several different groups, has drawn much attention in recent years. As a powerful tool, non-negative matrix factorization (NMF) has been applied successfully in clustering tasks. However, there
Xiang He, Qi Wang, Xuelong Li
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Clustering of Polysemic Words [PDF]

open access: yes, 2007
Cicurel L, Bloehdorn S, Cimiano P. Clustering of Polysemic Words. In: Decker R, Lenz H-J, eds. Advances in Data Analysis: Proceedings of the 30th Annual Conference of the German Classification Society (GfKl). Studies in Classification, Data Analysis, and
Lenz, Hans-Joachim   +7 more
core   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Sustainable Farming: Insights from Data Clustering

open access: yesЭкономика: стратегия и практика
This study delves into the perceptions and practices of the agricultural community regarding eco-friendly technologies and air pollution through a detailed clustering analysis of survey data.
A. Akhmetkyzy   +2 more
doaj   +1 more source

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