Results 91 to 100 of about 796,452 (265)

KIHCDP: An Incremental Hierarchical Clustering Approach for IoT Data Using Dirichlet Process

open access: yesIEEE Access
Internet of Things (IoT) devices are constantly producing vast amounts of data, necessitating efficient storage and processing to extract useful information. However, the models used to extract relevant information from IoT data are often hindered by the
Abishi Chowdhury   +3 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Informational Clustering of Hyperspectral Data

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2014
Hyperspectral remote sensing is recognized as a powerful tool for mineralogical mapping of exposed surfaces on Earth and planets, as well. It allows for more rigorous discrimination among materials than multispectral imaging. Nevertheless, the huge data volume that comes with single observations results in severe limitations to successful data ...
Loredana Pompilio   +3 more
openaire   +3 more sources

Educational Data Clustering in Secondary School Sensor-Based Engineering Courses Using Active Learning Approaches

open access: yesApplied Sciences
The authors investigated the impact of active learning STEM and STEAM approaches on secondary school students’ general engineering knowledge, intrinsic relevance, and creativity. Three out-of-school sensor-based courses were held successively.
Taras Panskyi   +2 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Photovoltaic Solar Power Prediction Using iPSO-Based Data Clustering and AdaLSTM Network

open access: yesEnergies
Due to the increasing integration of photovoltaic (PV) solar power into power systems, the prediction of PV solar power output plays an important role in power system planning and management. This study combines an optimized data clustering method with a
Jincun Liu, Kangji Li, Wenping Xue
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Topological Data Analysis and Clustering

open access: yes, 2023
This article is intended to be a chapter for a ...
openaire   +2 more sources

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