Results 181 to 190 of about 803,970 (265)
Hybrid raven roosting intelligence framework for enhancing efficiency in data clustering. [PDF]
Malik S +4 more
europepmc +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
scHNTL: single-cell RNA-seq data clustering augmented by high-order neighbors and triplet loss. [PDF]
Meng H, Qin C, Long Z.
europepmc +1 more source
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
GSTRPCA: irregular tensor singular value decomposition for single-cell multi-omics data clustering. [PDF]
Cui L, Guo G, Ng MK, Zou Q, Qiu Y.
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Time-domain and 3D methods for lung perfusion data clustering in electrical impedance tomography. [PDF]
Victor MH +5 more
europepmc +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Multi-level multi-view network based on structural contrastive learning for scRNA-seq data clustering. [PDF]
Shu Z, Xia M, Tan K, Zhang Y, Yu Z.
europepmc +1 more source

