Results 101 to 110 of about 5,902,886 (313)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Prenatal diagnostic testing and Down syndrome in Victoria 1992–2002
Australian and New Zealand Journal of Public Health, 2004 Objective:To describe patterns of uptake of prenatal diagnostic testing and prenatal detection rates for Down syndrome in Victoria with regard to mater nal age and prenatal screening practices.
Evelyne E. Muggli, Jane L. Halliday
doaj +1 more source
An Interview with Professor Lance Lanyon
Veterinary Evidence, 2016 Professor Lance Lanyon recently published an article in Veterinary Record (Lanyon, 2016) proposing a nationwide Evidence Based Veterinary Medicine (EBVM) system of veterinary-practice data collection, management and interrogation. The goal is to use data
Lance Lanyon
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Positive Feedback: Using Interlibrary Loan Transaction Log Data to Inform Collection Development
, 2013 The Associate Librarian for Access Services and Collection Management at Brown University Library requested an analysis of user and bibliographic data for faculty requests in the BorrowDirect and ILLiad systems to provide some insight on possible gaps in
Link, Forrest, Negrucci, Teresa
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
EDISThis publication is intended for scientists, technicians, and decision-makers who want to start using machine learning (ML) in their projects. It provides an overview of the factors that should be considered when employing ML applications with time ...
Eduart Murcia Botache, Sandra Guzman
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Patient Preference and AdherenceMelissa Culhane Maravic,1 Kelly Birch,1 Anh Thy H Nguyen,1 Alicia Subasinghe,2 Elizabeth Stafford,3 Christopher Zacker2 1Precision AQ, New York, NY, USA; 2Cerevel Therapeutics, Cambridge, MA, USA; 3National Alliance on Mental Illness, Arlington, VA ...
Maravic MC +5 more
doaj
Frontiers in Plant ScienceGynostemma pentaphyllum, a perennial medicinal herb, is widely distributed and exhibits remarkable adaptability to various environments. WRKY transcription factors play critical roles in regulating plant growth and development, as well as abiotic stress ...
Yunyi Zhou +13 more
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Reading Digital Fiction Project Hyperlink Study data
, 2017 These data were collected November 2016 at Bangor University, Bangor, Wales, UK, as part of the Reading Digital Fiction project study on hyperlinks. Nineteen people participated in the study. The significant data collection consisted of an audio-recorded
van der Bom, Isabelle +3 more
core +1 more source