Results 111 to 120 of about 5,902,886 (313)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Experiences with Higher-Risk Myelodysplastic Syndromes and Improving Patient-Centered Treatment Decision-Making: A Qualitative Study of Patients, Caregivers, and Providers

Cancer Management and Research
Melissa Culhane Maravic,1 Natalie Land,1 Nadya Prood,1 Claire Cagle,1 Suepattra G May,1 Katharine Batt,1,2 Eduardo J Sabate,3 Ngozi Afulezi,3 Teraneh Z Jhaveri,3 Tracey Iraca,4 Cosmina Hogea3 1Precision AQ, Bethesda, MD, USA; 2Sprouts Consulting, Ltd ...
Maravic MC, Land N, Prood N, Cagle C, May SG, Batt K, Sabate EJ, Afulezi N, Jhaveri TZ, Iraca T, Hogea C   +10 more
doaj  

Airbnb raw scraped data collection

Overview: Airbnb lists worldwide a selection of homes and boutique hotels available for booking holidays. The Urban Big Data Centre (UBDC) conducts a daily web scraping exercise for the Airbnb website, with the code for this exercise openly ...
Wang, Yang, Urban Big Data Centre (UBDC), Ves, Nick   +2 more
core  

TOAR data collection at station China Meteorological Administration (CMA01), China

, 2020
Collection of air quality (and meteorological) measurement data at station China Meteorological Administration (CMA01), China. These data were provided by Prof.Dr.
Xu Xiaobin, Chinese Academy of Meteorological Sciences (CAMS), China Meteorological Administration (CMA)   +1 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

TOAR data collection at station AKeDaLa (AKDL), China

, 2020
Collection of air quality (and meteorological) measurement data at station AKeDaLa (AKDL), China. These data were provided by Prof.Dr. Xiaobin Xu of Key Laboratory for Atmospheric Chemistry (KLAC), Chinese Academy of Meteorological Sciences (CAMS), China
Xu Xiaobin, Chinese Academy of Meteorological Sciences (CAMS), China Meteorological Administration (CMA)   +1 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Who Will Author the Synthetic Texts? Evoking Multiple Personas from Large Language Models to Represent Users’ Associative Thesauri

Big Data and Cognitive Computing
Previously, it was suggested that the “persona-driven” approach can contribute to producing sufficiently diverse synthetic training data for Large Language Models (LLMs) that are currently about to run out of real natural language texts. In our paper, we
Maxim Bakaev, Svetlana Gorovaia, Olga Mitrofanova   +2 more
doaj   +1 more source

TOAR data collection at station LinAn (LN58448), China

, 2020
Collection of air quality (and meteorological) measurement data at station LinAn (LN58448), China. These data were provided by Prof.Dr. Xiaobin Xu of Key Laboratory for Atmospheric Chemistry (KLAC), Chinese Academy of Meteorological Sciences (CAMS ...
Xu Xiaobin, Chinese Academy of Meteorological Sciences (CAMS), China Meteorological Administration (CMA)   +1 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source