Results 91 to 100 of about 24,372,621 (308)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Seismic Data Compression using Wave Atom Transform [PDF]
, 2015 Seismic data compression SDC is crucially confronted in the oil Industry with large data volumes and Incomplete data measurements In this research we present a comprehensive method of exploiting wave packets to perform seismic data compression Wave
E.Sreenivasa Reddy +2 more
core
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Information Loss in Binomial Data Due to Data Compression
Entropy, 2017 This paper explores the idea of information loss through data compression, as occurs in the course of any data analysis, illustrated via detailed consideration of the Binomial distribution.
Susan E. Hodge, Veronica J. Vieland
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Semantic trajectory compression: Representing urban movement in a nutshell
Journal of Spatial Information Science, 2012 There is an increasing number of rapidly growing repositories capturing the movement of people in space-time. Movement trajectory compression becomes an obvious necessity for coping with such growing data volumes.
Kai-Florian Richter +2 more
doaj +1 more source
On prediction by data compression [PDF]
, 1997 Traditional wisdom has it that the better a theory compresses the learning data concerning some phenomenon under investigation, the better we learn, generalize, and the better the theory predicts unknown data. This belief is vindicated in practice but apparently has not been rigorously proved in a general setting.
Vitanyi, P.M.B., Li, M.
openaire +2 more sources
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Photoacoustic-computed tomography 3D data compression method and system based on Wavelet-Transformer
Journal of Innovative Optical Health SciencesPhotoacoustic-computed tomography is a novel imaging technique that combines high absorption contrast and deep tissue penetration capability, enabling comprehensive three-dimensional imaging of biological targets.
Jialin Li +4 more
doaj +1 more source
Lossless compression of high-volume numerical data from simulations
, 2000 Summary form only given. We propose a lossless algorithm of delta compression (a variant of predictive coding) that attempts to predict the next point from previous points using higher-order polynomial extrapolation. In contrast to traditional predictive
Fritzson, Peter, +2 more
core +1 more source