Results 71 to 80 of about 368,925 (266)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Data Compression with a Time Limit

Algorithms
In this paper, we explore a framework to identify an optimal choice of compression algorithms that enables the best allocation of computing resources in a large-scale data storage environment: our goal is to maximize the efficiency of data compression ...
Bruno Carpentieri
doaj   +1 more source

Evaluation of Tunable Data Compression in Energy-Aware Wireless Sensor Networks

Sensors, 2010
Energy is an important consideration in wireless sensor networks. In the current compression evaluations, traditional indices are still used, while energy efficiency is probably neglected.
Beihua Ying, Yongpan Liu, Huazhong Yang, Hui Wang   +3 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Factorial Numbers and Their Practical Applications

Applied Sciences
This paper develops the theory of factorial numbers formed by positional number systems with mixed-base factorial number systems. The fundamentals of the theory of factorial numbers are outlined, a method for obtaining them is given, their range is ...
Oleksiy Borysenko, Oleksii Horiachev, Svitlana Matsenko, Anatolii Novhorodtsev, Olga Berezhna, Vjaceslavs Bobrovs, Toms Salgals, Jurgis Porins   +7 more
doaj   +1 more source

Sensor Data Compression Using Bounded Error Piecewise Linear Approximation with Resolution Reduction

Energies, 2019
Smart production as one of the key issues for the world to advance toward Industry 4.0 has been a research focus in recent years. In a smart factory, hundreds or even thousands of sensors and smart devices are often deployed to enhance product quality ...
Jeng-Wei Lin, Shih-wei Liao, Fang-Yie Leu   +2 more
doaj   +1 more source