Results 71 to 80 of about 21,889,530 (328)

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

FEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter, James Larson, Monika Tokmina‐Lukaszewska, Jin Xiong, Jared Green, Yisong Guo, William E. Broderick, Brian Bothner, Joan B. Broderick   +8 more
wiley   +1 more source

The cytochrome oxidase defect in ISC‐depleted yeast is caused by impaired iron–sulfur cluster maturation of the mitoribosome assembly factor Rsm22

FEBS Letters, EarlyView.
The yeast mitoribosome assembly factor Rsm22 contains a [4Fe‐4S] cluster that is matured by the mitochondrial iron–sulfur cluster assembly (ISC) machinery. Defects in ISC components result in impaired mitochondrial protein synthesis due to a mitoribosome assembly defect.
Ulrich Mühlenhoff, Dominik Trauth, Weronika Śliwińska, Linda Boss, Roland Lill   +4 more
wiley   +1 more source

An Improved Downlink MC-CDMA System for Efficient Image Transmission

Journal of Telecommunications and Information Technology, 2017
Image compression is an essential stage of the data archiving and transmitting process, as it reduces the number of bits and the time required to complete the transmission.
Mohammed Sofiane Bendelhoum, Ali Djebbari, Ismail Boukli-Hacene, Abdelmalik Taleb-Ahmed   +3 more
doaj   +1 more source

Technical analysis of ship integrated power system data compression based on improved swinging door algorithm

Zhongguo Jianchuan Yanjiu, 2020
Objectives In order to accumulate a ship's comprehensive power big data resources, especially in the case of relatively limited ship computing resources, and realize the effective compression of large-scale historical data, an improved revolving door ...
SHANG Chengya, BAO Xianqiang, FU Lijun, ZHU Wanlu, XU Xinghua   +4 more
doaj   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

A Survey on Data Compression Methods for Biological Sequences

Inf., 2016
The ever increasing growth of the production of high-throughput sequencing data poses a serious challenge to the storage, processing and transmission of these data. As frequently stated, it is a data deluge.
S. M. Hosseini, Diogo Pratas, A. Pinho
semanticscholar   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Evaluating lossy data compression on climate simulation data within a large ensemble

Geoscientific Model Development, 2016
. High-resolution Earth system model simulations generate enormous data volumes, and retaining the data from these simulations often strains institutional storage resources.
A. Baker, D. Hammerling, S. Mickelson, Haiying Xu, Martin B. Stolpe, P. Naveau, B. Sanderson, I. Ebert‐Uphoff, S. Samarasinghe, F. Simone, F. Carbone, C. N. Gencarelli, J. Dennis, J. Kay, Peter Lindstrom   +14 more
semanticscholar   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Compressed domain image resizing based on saliency histogram equalisation and seam carving

The Journal of Engineering, 2020
With the increasing popularity of mobile devices and internet services, resizing of compressed images is in high demand. In this study, a compressed domain content-aware image resizing (CAIR) system is proposed.
Hsi-Chin Hsin
doaj   +1 more source