Results 201 to 210 of about 25,162,578 (291)

An AI-powered data curation and publishing virtual assistant: usability and explainability/causability of, and patient interest in the first-generation prototype. [PDF]

Front Digit Health
van Mierlo R, Liang W, Norak K, Kargl M, Maasik M, Bynens AL, Plass M, Kreuzthaler M, Benedikt M, Hochstenbach L, van 't Hof A, Celebi R, Dekker A, de Zegher I, Kalendralis P, AIDAVA consortium.   +15 more
europepmc   +1 more source

Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella, Veria Vacchiano, Vittorio Velucci, Stefano Zoccolella, Rocco Liguori, Giovanni Defazio   +5 more
wiley   +1 more source

Machine Learning Modeling for ABC Transporter Efflux and Inhibition: Data Curation, Model Development, and New Compound Interaction Predictions. [PDF]

Mol Pharm
Daood NJ, Carey SR, Chung E, Wang T, Kreutz A, Girireddy M, Chakravarti S, Kleinstreuer NC, Tiley JB, Aleksunes LM, Zhu H.   +10 more
europepmc   +1 more source

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello, Francesca Serani, Alen Bebeti, Federica Paredi, Giulia Quadrio, Andrea Fortuna, Giacomo Maria Minicuci, Elena Pegoraro, Annachiara Cagnin, Diego Cecchin, Gianni Sorarù   +10 more
wiley   +1 more source

Multimodal data curation via interoperability: use cases with the Medical Imaging and Data Resource Center. [PDF]

Sci Data
Chen W, Whitney HM, Kahaki S, Meyer C, Li H, Sá RC, Lauderdale D, Napel S, Gersing K, Grossman RL, Giger ML.   +10 more
europepmc   +1 more source

Avant-garde: an automated data-driven DIA data curation tool. [PDF]

Nat Methods, 2020
Vaca Jacome AS, Peckner R, Shulman N, Krug K, DeRuff KC, Officer A, Christianson KE, MacLean B, MacCoss MJ, Carr SA, Jaffe JD.   +10 more
europepmc   +1 more source

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez, Fareshte Erani, Katherine J. Bangen, David G. Coughlin, Douglas Galasko, Kelsey R. Thomas   +5 more
wiley   +1 more source

A large dataset of brain imaging linked to health systems data: curation and access to a whole system national cohort from NHS Scotland. [PDF]

Gigascience
Camilleri MPJ, Gouzou D, Al-Wasity S, Mookiah MRK, Hernandez MV, Alex B, Tsaftaris SA, Brooks A, MacLeod R, Wu H, Bauer B, Grover C, Reel P, Krueger S, Tobin R, Steele JD, Mair G, Wardlaw J, Doney A, Trucco E, Whiteley W.   +20 more
europepmc   +1 more source

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

Preserving noise texture through training data curation for deep learning denoising of high-resolution cardiac EID-CT. [PDF]

Med Phys
Treb K, Chang S, Koons E, Marsh J, Foley T, Williamson E, McCollough C, Leng S.   +7 more
europepmc   +1 more source