Results 81 to 90 of about 2,018,475 (309)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Making Qualitative Data Fit the "Data Documentation Initiative" or Vice Versa?

open access: yesForum: Qualitative Social Research, 2000
The Finnish Social Science Data Archive is a newcomer in the area of data archiving for two reasons, firstly: it started its operation only in 1999 and secondly: from the very beginning it has had as an official strategy to enhance the reuse of available
Arja Kuula
doaj  

Guidelines for submitting data to the National Space Science Data Center [PDF]

open access: yes
The mission of the National Space Science Data Center (NSSDC) is to disseminate space science data for further analysis beyond that provided by the principal investigators (PIs) or team leaders (TLs) and their coworkers.

core   +1 more source

MetExploreViz: web component for interactive metabolic network visualization [PDF]

open access: yes, 2017
Summary: MetExploreViz is an open source web component that can be easily embedded in any web site. It provides features dedicated to the visualization of metabolic networks and pathways and thus offers a flexible solution to analyse omics data in a ...
Chazalviel, Maxime   +7 more
core   +4 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Ancillary Documentation on the Union Army Migration Data set (UMAD) [PDF]

open access: yes
migration; economic history; economics of ...
M. A. Sanchez
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Mariner 9 infrared interferometer spectrometer (IRIS) reduced data records documentation [PDF]

open access: yes
The Mariner 9 spacecraft was successfully inserted into orbit around Mars. One of the five instruments on board, an infrared interferometer spectrometer is used to record the thermal emission spectrum of Mars between 200 and 2000 cm/1.

core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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