Results 41 to 50 of about 29,187 (266)
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Secure Access Control to Data in Off-Chain Storage in Blockchain-Based Consent Systems
Data access control is a crucial aspect of data management. Actors who want to share data need systems to manage consent in order to decide who can access their data. This guarantees the privacy of data, which is often sensitive.
Mongetro Goint +2 more
doaj +1 more source
Computing on Encrypted Data [PDF]
Encryption secures our stored data but seems to make it inert. Can we process encrypted data without having to decrypt it first? Answers to this fundamental question give rise to a wide variety of applications. Here, we explore this question in a number of settings, focusing on how interaction and secure hardware can help us compute on encrypted data ...
openaire +1 more source
Encrypted Shared Data Spaces [PDF]
The deployment of Share Data Spaces in open, possibly hostile, environments arises the need of protecting the confidentiality of the data space content. Existing approaches focus on access control mechanisms that protect the data space from untrusted agents.
Giovanni Russello +4 more
openaire +3 more sources
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Healthcare institutions generate massive amounts of valuable patient data in the digital age. Finding the right balance between patient privacy and the demand for data-driven medical enhancements is essential.
Marios Vardalachakis +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source

