Results 111 to 120 of about 7,552,821 (296)

Data flow within global clinical trials: a scoping review. [PDF]

open access: yesBMJ Glob Health, 2022
Kwok K, Sati N, Dron L, Murthy S.
europepmc   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Improved flow prediction of non-ideal sonic nozzles by CFD-based surrogate modelling

open access: yesEngineering Applications of Computational Fluid Mechanics
The use of sonic nozzles as a high-precision standard for gas flow measurements in various engineering and metrological applications is well-established.
Sebastian Weiss   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A data flow process for confidential data and its application in a health research project. [PDF]

open access: yesPLoS One, 2022
Crossfield SSR   +8 more
europepmc   +1 more source

Fixed Boundary Flows

open access: yes, 2019
We consider the fixed boundary flow with canonical interpretability as principal components extended on the non-linear Riemannian manifolds. We aim to find a flow with fixed starting and ending point for multivariate datasets lying on an embedded non ...
Fan, Zengyan, Xia, Yuqing, Yao, Zhigang
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Enhancing the interoperability of glycan data flow between ChEBI, PubChem and GlyGen. [PDF]

open access: yesGlycobiology, 2021
Navelkar R   +12 more
europepmc   +1 more source

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