Results 111 to 120 of about 5,283,237 (295)

Sex-Biased Gene Flow Among Elk in the Greater Yellowstone Ecosystem [PDF]

open access: yes, 2014
We quantified patterns of population genetic structure to help understand gene flow among elk populations across the Greater Yellowstone Ecosystem.
Anderson, Neil   +16 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

New Benchmarking Methodology and Programming Model for Big Data Processing

open access: yesInternational Journal of Distributed Sensor Networks, 2015
Big data processing is becoming a reality in numerous real-world applications. With the emergence of new data intensive technologies and increasing amounts of data, new computing concepts are needed.
Anton Kos   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Strategies for concurrent processing of complex algorithms in data driven architectures [PDF]

open access: yes
The results of ongoing research directed at developing a graph theoretical model for describing data and control flow associated with the execution of large grained algorithms in a spatial distributed computer environment is presented.
Mielke, Roland R., Stoughton, John W.
core   +4 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Data Flow Architecture for Advanced Process Control

open access: yesIFAC Proceedings Volumes, 1994
Abstract A data flow approach to the integration of numerical and non-numerical computations for real-time process control is presented. Process models and control algorithms are encapsulated in data flow functions communicating via streams conveying time-discrete data.
openaire   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Optimized Data-Flow Integrity for Modern Compilers

open access: yesIEEE Access
Non-control-data attacks are those attacks that purely target and modify the non-control data of a program, such as boolean values, user input or configuration parameters, and leave the control flow of a program untouched. These attacks were considered a
Irene Diez-Franco   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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