Results 71 to 80 of about 35,264 (209)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Lightweight Transformer-Based Spatiotemporal Analysis Prediction Algorithm for High-Dimensional Meteorological Data

Remote Sensing
High-dimensional meteorological data offer a comprehensive overview of meteorological conditions. Nevertheless, predicting regional high-dimensional meteorological data poses challenges due to the vast scale and rapid changes.
Yinghao Tan, Junfeng Wu, Yihang Liu, Shiyu Shen, Xia Xu, Bin Pan   +5 more
doaj   +1 more source

Processing of Extremely High Resolution LiDAR and RGB Data: Outcome of the 2015 IEEE GRSS Data Fusion Contest—Part B: 3-D Contest

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2016
In this paper, we report the outcomes of the 2015 data fusion contest organized by the Image Analysis and Data Fusion Technical Committee (IADF TC) of the IEEE Geoscience and Remote Sensing Society.
A.-V. Vo, L. Truong-Hong, D. F. Laefer, D. Tiede, S. dOleire-Oltmanns, A. Baraldi, M. Shimoni, G. Moser, D. Tuia   +8 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Reviews of Geospatial Information Technology and Collaborative Data Delivery for Disaster Risk Management

ISPRS International Journal of Geo-Information, 2015
Due to the fact that geospatial information technology is considered necessary for disaster risk management (DRM), the need for more effective collaborations between providers and end users in data delivery is increasing. This paper reviews the following:
Hiroyuki Miyazaki, Masahiko Nagai, Ryosuke Shibasaki   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Benchmarking Multimodal Deep Fusion Strategies for Heterogeneous Neuroimaging and Cognitive Data Using a Controlled Sex Classification Task

Brain Sciences
Background/Objectives: Multimodal data fusion is increasingly applied in neuroinformatics to integrate heterogeneous sources of information. However, the optimal strategies for combining modalities with markedly different dimensionality, scale, and noise
Chiara Camastra, Assunta Pelagi, Andrea Quattrone, Alessia Sarica   +3 more
doaj   +1 more source

Framework of SAGI Agriculture Remote Sensing and Its Perspectives in Supporting National Food Security

Journal of Integrative Agriculture, 2014
Remote sensing, in particular satellite imagery, has been widely used to map cropland, analyze cropping systems, monitor crop changes, and estimate yield and production.
Yun SHI, Shun-ping JI, Xiao-wei SHAO, Hua-jun TANG, Wen-bin WU, Peng YANG, Yong-jun ZHANG, Shibasaki Ryosuke   +7 more
doaj   +1 more source