Results 81 to 90 of about 25,248,396 (296)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Processing on Structural Data Faultage in Data Fusion

Data, 2020
With the rapid development of information technology, the development of information management system leads to the generation of heterogeneous data. The process of data fusion will inevitably lead to such problems as missing data, data conflict, data ...
Fan Chen, Ruoqi Hu, Jiaoxiong Xia, Jie Tao   +3 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Fusion of optical and radar remote sensing data: Munich city example [PDF]

, 2010
Fusion of optical and radar remote sensing data is becoming an actual topic recently in various application areas though the results are not always satisfactory.
Palubinskas, Gintautas, Reinartz, Peter
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Studies on D-3^He Fusion in LHD [PDF]

, 1996
In LHD ( Large Helical Device ) studies on realization of D-D fusion burning has been carried out, where tritium burning is out of this plan. We propose experiments on D-^3He fusion in this plan. This fueled fusion has the reaction cross-section as large
YAMAZAKI, Kozo, FUJIWARA, Masami, IIYOSHI, Atsuo, SUDO, Shigeru, MURAKAMI, Sadayoshi, KANNO, Ryutaro, TOMITA, Yukihiro, OHYABU, Nobuyoshi, SASAO, Mamiko, OKAMOTO, Masao, KANEKO, Osamu, TAKEIRI, Yasuhiko, MUTOH, Takashi   +12 more
core  

Efficient training sets for surrogate models of tokamak turbulence with Active Deep Ensembles

Nuclear Fusion
Model-based plasma scenario development lies at the heart of the design and operation of future fusion powerplants. Including turbulent transport in integrated models is essential for delivering a successful roadmap towards operation of ITER and the ...
L. Zanisi, A. Ho, J. Barr, T. Madula, J. Citrin, S. Pamela, J. Buchanan, F.J. Casson, V. Gopakumar, JET Contributors   +9 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Design of Intense Neutron Source for Fusion Material Study and the Role of Universities [PDF]

, 1993
Need and requirement for the intense neutron source for fusion materials study have been discussed for many years. Recently, international climate has been becoming gradually maturing to consider this problem more seriously because of the recognition of ...
ISHINO, Shiori
core  

Medical image fusion: A survey of the state of the art [PDF]

, 2014
Medical image fusion is the process of registering and combining multiple images from single or multiple imaging modalities to improve the imaging quality and reduce randomness and redundancy in order to increase the clinical applicability of medical ...
James, Alex Pappachen, Alex Pappachen, James, Dasarathy, Belur V.   +2 more
core   +1 more source