Results 81 to 90 of about 26,250,201 (307)

Development of JAERI Monte Carlo machine and its effective performance

Computer Assisted Methods in Engineering and Science, 2023
The JAERI Monte Carlo Machine has been developed mainly to enhance the computational performance of numerical simulations with particle models such as Monte Carlo methods. The features of the JAERI Monte Carlo machine are i) vector processing capability
Kenji Higuchi, Kiroshi Asai, Masayuki Akimoto, Shaw Kambayashi, Shinji Tokuda, Yukihiro Hasegawa, Akira Asami, Makoto Sasaki   +7 more
doaj  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Challenges and Countermeasures of Federated Learning Data Poisoning Attack Situation Prediction

Mathematics
Federated learning is a distributed learning method used to solve data silos and privacy protection in machine learning, aiming to train global models together via multiple clients without sharing data.
Jianping Wu, Jiahe Jin, Chunming Wu
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Multi-Modal and Multi-Temporal Data Fusion: Outcome of the 2012 GRSS Data Fusion Contest

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2013
The 2012 Data Fusion Contest organized by the Data Fusion Technical Committee (DFTC) of the IEEE Geoscience and Remote Sensing Society (GRSS) aimed at investigating the potential use of very high spatial resolution (VHR) multi-modal/multi-temporal image ...
Christian Berger, Michael Voltersen, Robert Eckardt, Jonas Eberle, Thomas Heyer, Nesrin Salepci, Soren Hese, Christiane Schmullius, Junyi Tao, Stefan Auer, Richard Bamler, Ken Ewald, Michael Gartley, John Jacobson, Alan Buswell, Qian Du, Fabio Pacifici   +16 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Processing on Structural Data Faultage in Data Fusion

Data, 2020
With the rapid development of information technology, the development of information management system leads to the generation of heterogeneous data. The process of data fusion will inevitably lead to such problems as missing data, data conflict, data ...
Fan Chen, Ruoqi Hu, Jiaoxiong Xia, Jie Tao   +3 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Efficient training sets for surrogate models of tokamak turbulence with Active Deep Ensembles

Nuclear Fusion
Model-based plasma scenario development lies at the heart of the design and operation of future fusion powerplants. Including turbulent transport in integrated models is essential for delivering a successful roadmap towards operation of ITER and the ...
L. Zanisi, A. Ho, J. Barr, T. Madula, J. Citrin, S. Pamela, J. Buchanan, F.J. Casson, V. Gopakumar, JET Contributors   +9 more
doaj   +1 more source