Results 161 to 170 of about 24,536,364 (296)

Data Governance

Toshiya Watanabe, Tadashi Mima
  +8 more sources

Māori Research Data Governance in New Zealand Universities. [PDF]

J R Soc N Z
West K, Renfrew L.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Evaluating the Quality and Impact of Online Patient Forums in Genomic Data Governance. [PDF]

Health Expect
Eric A, Christoph S, Züger A, Winkler EC, Katja M.   +4 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Data for: Corporate Governance, Home Country Governance, and MNE CSR: Evidence from Ghana

This dataset is related to a sample of 360 firm-year observations pertaining to 44 subsidiaries of foreign MNEs operating in Ghana from 2010 to 2018.
Chen, Junxin, Chen, J (via Mendeley Data)   +1 more
core   +1 more source

Promoting self-determined Indigenous data governance in Canada: the Métis Health Research and Data Governance Principles. [PDF]

Health Promot Int
Henry R, Gabel C, Tait C, Kowalski K, Nychuk A.   +4 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Data governance framework for artificial intelligence

大数据
Data plays a crucial role in the development and application of artificial intelligence, which has become a consensus in industry and academia. Based on the interactive relationship between artificial intelligence and data, as well as the data-centric AI
LI Jifeng, ZHANG Chenglong, LIU Xin, CHEN Jinyu, ZHANG Jinming, BI Chao   +5 more
doaj   +2 more sources

Responsible workplace data governance and organizational performance: evidence from Chinese listed firms. [PDF]

Front Psychol
Chen L.
europepmc   +1 more source