Results 181 to 190 of about 295,101 (300)

BRIDGE pilot study: a bilateral regulatory investigation of data governance and exchange. [PDF]

NPJ Digit Med
Hou HX, Bisson T, Leiss SM, Thierauf J, Stern AD, Strobelt H, Nensa F, Buyx A, Huster KM, Furlano K, Kozlakidis Z, Gupta S, Kostadinov D, Boor P, Slagman A, Tjardes T, Cholet P, Schneider NK, Schlomm T, Biskup S, Röhrig R, Molnár-Gábor F, Schmidt-Straßburger U, Ladewig K, Weigand M, Pinto Dos Santos D, Johnson JM, Kirsten T, Sutherland E, Zerbe N, Hofman A, Heyder R, Schmidt G, Lennerz JK.   +33 more
europepmc   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Principles and Policy Recommendations for Comprehensive Genetic Data Governance. [PDF]

Proc AAAI ACM Conf AI Ethics Soc
Ramanan V, Vinod R, Williams C, Ramachandran S, Venkatasubramanian S.   +4 more
europepmc   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Increasing Innu participation in public health: a qualitative study of data governance among Innu in Labrador, Canada. [PDF]

BMJ Public Health
Ward LM, Heffernan C, Alvarez GG, Picard A, Carrington A, Long R.   +5 more
europepmc   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Medico-legal considerations in post-mortem imaging data: governance, ethics, and evidential use. [PDF]

BJR Open
Davendralingam N, Shelmerdine SC, Brookes AL, Jones I.   +3 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Medical Imaging Data Calls for a Thoughtful and Collaborative Approach to Data Governance. [PDF]

PLOS Digit Health
Lutz de Araujo A, Wu J, Harvey H, Lungren MP, Graham M, Leiner T, Willemink MJ.   +6 more
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source