Results 201 to 210 of about 158,842 (252)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Generalisable Overview of Study Risk for Lead Investigators Needing Guidance (GOSLING): A data governance risk tool. [PDF]

open access: yesPLoS One
Arora A   +8 more
europepmc   +1 more source

Open Data governance at the Canadian Open Neuroscience Platform (CONP): From the Walled Garden to the Arboretum. [PDF]

open access: yesGigascience
Bernier A   +6 more
europepmc   +1 more source
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Government data governance framework based on a data middle platform

Aslib Journal of Information Management, 2021
PurposeThe present paper constructed a new framework for government data governance based on the concept of a data middle platform to elicit the detailed requirements and functionalities of a government data governance framework.Design/methodology/approachFollowing a three-cycle activity, the design science research (DSR) paradigm was used to develop ...
Zijun Mao   +3 more
openaire   +1 more source

Data governance for SoS

International Journal of System of Systems Engineering, 2012
Data governance is a central element in a system of systems (SoS). Data governance includes clearly defined authority to create and enforce data policies and procedures within a SoS. Without formal data governance, disconnected and unregulated data requirements within the constituent sub-systems often result in duplicative data storage, invalid data ...
Debra Wilbanks, Karen Lehman
openaire   +1 more source

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