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The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
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Digital twins in sustainable transition: exploring the role of EU data governance. [PDF]
Garske B, Holz W, Ekardt F.
europepmc +1 more source
Data as an economic good, data as a commons, and data governance. [PDF]
Purtova N, van Maanen G.
europepmc +1 more source
Generalisable Overview of Study Risk for Lead Investigators Needing Guidance (GOSLING): A data governance risk tool. [PDF]
Arora A +8 more
europepmc +1 more source
Open Data governance at the Canadian Open Neuroscience Platform (CONP): From the Walled Garden to the Arboretum. [PDF]
Bernier A +6 more
europepmc +1 more source
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Government data governance framework based on a data middle platform
Aslib Journal of Information Management, 2021PurposeThe present paper constructed a new framework for government data governance based on the concept of a data middle platform to elicit the detailed requirements and functionalities of a government data governance framework.Design/methodology/approachFollowing a three-cycle activity, the design science research (DSR) paradigm was used to develop ...
Zijun Mao +3 more
openaire +1 more source
International Journal of System of Systems Engineering, 2012
Data governance is a central element in a system of systems (SoS). Data governance includes clearly defined authority to create and enforce data policies and procedures within a SoS. Without formal data governance, disconnected and unregulated data requirements within the constituent sub-systems often result in duplicative data storage, invalid data ...
Debra Wilbanks, Karen Lehman
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Data governance is a central element in a system of systems (SoS). Data governance includes clearly defined authority to create and enforce data policies and procedures within a SoS. Without formal data governance, disconnected and unregulated data requirements within the constituent sub-systems often result in duplicative data storage, invalid data ...
Debra Wilbanks, Karen Lehman
openaire +1 more source

