Results 251 to 260 of about 26,063,590 (386)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Data Governance.

open access: yes, 2014
Data is the lifeblood of any business and is a valued resource and an asset. Good data governance means that all data has a designated owner (usually someone senior in the organisation) to ensure it is managed and looked after as a financial asset. Good data governance can drive efficiencies and enhance public services, whilst at the same time reducing
openaire   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Health data hubs: an analysis of existing data governance features for research. [PDF]

open access: yesHealth Res Policy Syst, 2023
Alvarez-Romero C   +3 more
europepmc   +1 more source

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