Results 281 to 290 of about 26,063,590 (386)

Get Started in Data Governance and Data Stewardship

Atikah Hanisah Mohd Hanif, Xin Yi Lew, Muhammad Haziq Ibrahim, Doris Hooi-Ten Wong   +3 more
openalex   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Editorial: Data governance in African health research: ELSI challenges and solutions. [PDF]

Front Pharmacol
Thaldar D.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Data governance and open sharing in the fields of life sciences and medicine: A bibliometric analysis. [PDF]

Digit Health
Qiu Y, Hu Z.
europepmc   +1 more source

Ξ_SeminarWorkshop_Standardmodul_v1 – Data-Free Governance & Workshop Framework

Brueckner, Winfried
openalex   +1 more source

A Comprehensive AI-Powered Survey Platform for Streamlining Data Collection,Analytical Power for Smart E-Governance [PDF]

Eshan Bhakare, Aniket Prajapati, Vedant Chaudhari, Kanishk Chaudhary, Alka Kumbhar   +4 more
openalex   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Blockchain-enabled data governance for privacy-preserved sharing of confidential data. [PDF]

PeerJ Comput Sci
Zhang J, Datta A.
europepmc   +1 more source

Multi-Level Governance in Humanitarian Organizations: Implications for Information Flows and Data Analytics

, 2015
Carleen Maitland
openalex   +1 more source