Results 51 to 60 of about 179,516 (314)

Long-Term Missing Value Imputation for Time Series Data Using Deep Neural Networks [PDF]

, 2022
Jangho Park, Juliane Müller, Bhavna Arora, Boris Faybishenko, Gilberto Pastorello, Charuleka Varadharajan, Reetik Kumar Sahu, D. Agarwal   +7 more
openalex   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Missing-Data Handling Methods for Lifelogs-Based Wellness Index Estimation: Comparative Analysis With Panel Data

JMIR Medical Informatics, 2020
BackgroundA lifelogs-based wellness index (LWI) is a function for calculating wellness scores based on health behavior lifelogs (eg, daily walking steps and sleep times collected via a smartwatch).
Kim, Ki-Hun, Kim, Kwang-Jae
doaj   +1 more source

Optimal Recovery of Missing Values for Non-Negative Matrix Factorization

IEEE Open Journal of Signal Processing, 2021
Missing values imputation is often evaluated on some similarity measure between actual and imputed data. However, it may be more meaningful to evaluate downstream algorithm performance after imputation than the imputation itself.
Rebecca Chen Dean, Lav R. Varshney
doaj   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen, Wenting Huang, Yitian Liu, Xuan Chen, Buyu Ke, Qian Shen, Hanyu Cai, Jing Sun, Yan Li, Yungang Cao, Beilei Hu, Keyang Chen   +11 more
wiley   +1 more source

weIMPUTE: a user-friendly web-based genotype imputation platform

Frontiers in Genetics
BackgroundGenotype imputation is a critical preprocessing step in genome-wide association studies (GWAS), enhancing statistical power for detecting associated single nucleotide polymorphisms (SNPs) by increasing marker size.ResultsIn response to the ...
Mingliang Li, Mingliang Li, Zhuo Li, Zhuo Li, Zhuo Li, Defu Liu, Qi Li, Xiaodong Hu, Jun Yu, Jian Lin, Chunguang Bi, Guanshi Ye, Helong Yu, You Tang, You Tang, You Tang   +15 more
doaj   +1 more source

Multiple imputation for handling missing outcome data when estimating the relative risk

BMC Medical Research Methodology, 2017
Background Multiple imputation is a popular approach to handling missing data in medical research, yet little is known about its applicability for estimating the relative risk.
Thomas R. Sullivan, Katherine J. Lee, Philip Ryan, Amy B. Salter   +3 more
doaj   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund, Johan Reutfors, Thomas Frisell, Fredrik Piehl   +3 more
wiley   +1 more source

Optimizing genotype imputation pipeline for low-coverage whole genome sequencing data in spotted sea bass and its application in genomic prediction

Aquaculture Reports
Genotype imputation following low-coverage whole genome sequencing (lcWGS) data offers a cost-effective approach for genotyping large populations, with significant potential to accelerate genomic selection in breeding programs.
Chong Zhang, Yonghang Zhang, Pengyu Li, Cong Liu, Lingyu Wang, Yani Dong, Donglei Sun, Xin Qi, Haishen Wen, Kaiqiang Zhang, Shaosen Yang, Yun Li   +11 more
doaj   +1 more source