Results 61 to 70 of about 4,439,564 (294)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Ten meter walk test with mobile devices: A dataset with accelerometer, magnetometer, and gyroscope

Data in Brief
This paper presents a dataset related to the performance of the Ten Meter Walking Test, a test to allow locomotor capacity in different research and clinical settings. One of the most important parameters to measure is the gait speed during a path of ten
Cristiana Lopes Gabriel, Ivan Miguel Pires, Norberto Jorge Gonçalves, Paulo Jorge Coelho, Eftim Zdravevski, Petre Lameski, Carlos Albuquerque, Nuno M. Garcia, Carlos Carreto   +8 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Gyroscope sensor data of shank motion during normal and barefoot walking

Data in Brief
In recent years, shank angular velocity (SAV) has emerged as a valuable tool for accurate temporal gait analysis and motion pattern assessment. To explore SAV among healthy subjects and its capability to distinguish differences between walking conditions,
Mikko Salminen, Saku Suominen, Akihiro Inomata, Shinji Hotta, Yuki Sasamoto, Lea Saarni, Antti Vehkaoja   +6 more
doaj   +1 more source

The Emergence of Big Data Policing [PDF]

, 2017
The past decade has seen both the proliferation of surveillance in everyday life and the rise of “big data.” Through extensive qualitative research focusing on the Los Angeles Police Department (LAPD), PRC faculty research associate Sarah Brayne explores
Brayne, Sarah
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The complete mitogenome dataset of the Critically Endangered estuarine pipefish, Syngnathus watermeyeri

Data in Brief
The Critically Endangered South African estuarine pipefish, Syngnathus watermeyeri, is one of the rarest teleost fish on the planet. In this analysed dataset, the complete mitochondrial genome of this species was assembled, annotated, and described.
Arsalan Emami-Khoyi
doaj   +1 more source

Arkansas Teacher Supply [PDF]

, 2018
This brief examines teacher supply in Arkansas. Using survey data collected in Spring 2017 and data publicly available from the Arkansas Department of Education, we examine how teacher supply varies by district, grade level, and subject across the state.
McKenzie, Sarah C.
core   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Data driven models on load forecasting: Case study Algeria

Data in Brief
Databases are indispensable in many areas. This historical database contains a wealth of information, such as the energy. Energy is a vital resource in our daily lives, for both residential and industrial users.
Rania Farah, Brahim Farou, Zineddine Kouahla, Hamid Seridi   +3 more
doaj   +1 more source