Results 131 to 140 of about 28,387,539 (314)
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Institute on Community Integration Annual Report: 1994-95
, 1995 The annual report summarizing the work and community impact of the Institute on Community Integration, a federally–designated University Affiliated Program on Developmental Disabilities working to improve community services and social supports for ...
Institute on Community Integration
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More than rapid identification—Free plant identification apps can also be highly accurate
People and NatureHart et al. (2023) conducted a study to evaluate the accuracy of five plant identification apps based on snapshot images as used in practice by field ecologists. Their results revealed varying accuracies per app, ranging from 86.9% to 46.4%.
Michael Rzanny +6 more
doaj +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
The Integration Barometer 2005 - 2013/14
The Integration Barometer identifies and measures people's attitudes about immigration, integration and diversity in Norway. The Integration Barometer was conducted for the first time in 2005 and this year's study represents the seventh. In 2013/2014 the
The Directorate of Integration and Diversity
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Institute on Community Integration Annual Report: 1995-96
, 1996 The annual report summarizing the work and community impact of the Institute on Community Integration, a federally–designated University Affiliated Program on Developmental Disabilities working to improve community services and social supports for ...
Institute on Community Integration
core
Clinical data integration approach using SAS clinical data integration server (CDI) tools [PDF]
, 2011 The decisions people make about medical treatments have a great impact on their lives. Health care practitioners, providers and patients often make decisions about medical treatments without complete understanding of the circumstances.
Nugawela, Saliya, Sahama, Tony R.
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source