Results 81 to 90 of about 28,387,539 (314)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Replication Data for: Urine Osmolality Assessment through the Integration of Urea Hydrolysis and Impedance Measurement

open access: yes
Replication Data for: Urine Osmolality Assessment through the Integration of Urea Hydrolysis and Impedance ...
Shen, Xinhui, Marcos, Kong, Tian Fook
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Approximate Integration of Streaming Data [PDF]

open access: yes, 2019
17 pages;Revue des Nouvelles Technologies de l'Information ...
Michel de Rougemont, Guillaume Vimont
openaire   +4 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Data integration in mediated service compositions [PDF]

open access: yes, 2012
A major aim of the Web service platform is the integration of existing software and information systems. Data integration is a central aspect in this con- text.
Zhu, Yaoling, Pahl, Claus
core  

Effective Data Management and Spatial Analytics

open access: yes, 2021
This webinar introduced the implementations of effective data management and spatial analytics by academic and industry leaders of the field, and discuss the directions for further enhancement through integration with a cloud-based platform for research ...
Spatial Data Lab
core   +1 more source

Leveraging electronic medical records to evaluate a computerized decision support system for staphylococcus bacteremia

open access: yesnpj Digital Medicine
Infectious disease specialists (IDS) improve outcomes of patients with Staphylococcus bacteremia, but immediate IDS access is not always guaranteed. We investigated whether a care-integrated computerized decision support system (CDSS) can safely enhance ...
Julia Palm   +50 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The MOMIS-STASIS approach for Ontology-Based Data Integration

open access: yes, 2009
Ontology based Data Integration involves the use of ontology(s) to effectively combine data and information from multiple heterogeneous sources. Ontologies can be used in an integration task to describe the semantics of the information sources and to ...
PO, Laura   +3 more
core  

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