Results 71 to 80 of about 1,389,848 (316)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Safeguarding integrity: a guide to the integrity system in Victoria [PDF]
, 2014 The Safeguarding Integrity Guide aims to help public sector employees and the broader community understand Victoria\u27s integrity system and its key agencies.
core
A Secure-Enhanced Data Aggregation Based on ECC in Wireless Sensor Networks
Sensors, 2014 Data aggregation is an important technique for reducing the energy consumption of sensor nodes in wireless sensor networks (WSNs). However, compromised aggregators may forge false values as the aggregated results of their child nodes in order to conduct ...
Qiang Zhou, Geng Yang, Liwen He
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Blockchain Beyond Cryptocurrency: Emerging Applications in Secure Data Sharing [PDF]
Iranian Journal of Information Processing & ManagementBackground: Blockchain, mainly known for supporting cryptocurrencies, has a much broader role, as seen in this paper. These fundamental features of decentralization and immutability guarantee improved security and transparency in multiple spheres of ...
Mohammed Abdul Jaleel Maktoof +4 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
International Research Integrity Survey, 2021
, 2022 copyright UK Data Service and data collection copyright owner.The International Research Integrity Survey (IRIS) is a large, cross-national survey of researchers in all EU member states and selected OECD countries on the topic of research integrity.
Allum, N., University of Essex +1 more
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Data management and the research record in research misconduct investigations [PDF]
, 2015 Presented at the National data integrity conference: enabling research: new challenges & opportunities held on May 7-8, 2015 at Colorado State University, Fort Collins, Colorado.
Busch, Kenneth L., author +1 more
core +1 more source
Integrating IoT, Artificial Intelligence, and Blockchain Technologies for the Development of Smart Networks [PDF]
Iranian Journal of Information Processing & ManagementBackground: IoT Smart networks are the latest creation of smart technology where Internet of Things, Artificial Intelligence, and Blockchain technologies have merged.
Sura Sabah +4 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source