Results 81 to 90 of about 1,390,426 (316)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Data management and the research record in research misconduct investigations [PDF]

open access: yes, 2015
Presented at the National data integrity conference: enabling research: new challenges & opportunities held on May 7-8, 2015 at Colorado State University, Fort Collins, Colorado.
Busch, Kenneth L., author   +1 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Intercut 2012 [PDF]

open access: yes, 2012
The surface integrity plays a very important rule in this functional performance, being dependent of a large number of machining parameters. The major concern of the industry is to know which combination of machining parameters provides a better surface ...
OUTEIRO, José   +1 more
core  

Trust threads: minimal provenance and data publication and reuse [PDF]

open access: yes, 2015
Presented at the National data integrity conference: enabling research: new challenges & opportunities held on May 7-8, 2015 at Colorado State University, Fort Collins, Colorado.
Plale, Beth, author   +1 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A brief history of unicorn husbandry and other magical wonders: data and the library [PDF]

open access: yes, 2016
Presented at the National data integrity conference: data sharing: the how, why, when and when not to share held on June 2-3, 2016 at University of Colorado, Denver, Colorado.
Wirz, Jackie, author   +1 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Link integrity for the Semantic Web [PDF]

open access: yes, 2012
The usefulness and usability of data on the Semantic Web is ultimately reliant on the ability of clients to retrieve Resource Description Framework (RDF) data from the Web.
Vesse, Robert
core  

Public health monitoring and research: experience with electronic health record data [PDF]

open access: yes, 2016
Presented at the National data integrity conference: data sharing: the how, why, when and when not to share held on June 2-3, 2016 at University of Colorado, Denver, Colorado.
Zucker, Rachel, author   +1 more
core   +1 more source

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