Results 101 to 110 of about 1,389,848 (316)
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Data Warehouse and Big Data Integration
Big Data triggered furthered an influx of research and prospective on concepts and processes pertaining previously to the Data Warehouse field. Some conclude that Data Warehouse as such will disappear; others present Big Data as the natural Data Warehouse evolution (perhaps without identifying a clear division between the two); and finally, some others
Salinas, Sonia Ordoñez +1 more
openaire +2 more sources
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Opportunities and challenges of data sharing in an academic research computing environment
Presented at the National data integrity conference: data sharing: the how, why, when and when not to share held on June 2-3, 2016 at University of Colorado, Denver, Colorado.
Hauser, Thomas, author
core +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Harnessing the data revolution: a perspective from the National Science Foundation
Presented at the National data integrity conference: data sharing: the how, why, when and when not to share held on June 2-3, 2016 at University of Colorado, Denver, Colorado.
Baru, Chaitan, author
core +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
TPA Ensuring Data Integrity in Cloud Environment
Cloud computing is an internet based computing where virtual shared servers provide software, infrastructure, platform and other resources to customers on a pay-as-you-use basis. In one of the services offered by cloud viz.
Jasmeet Singh
core

