Results 121 to 130 of about 1,389,848 (316)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Collaborative data sharing in climate science: acknowledgement, transparency, and provenance

, 2016
Presented at the National data integrity conference: data sharing: the how, why, when and when not to share held on June 2-3, 2016 at University of Colorado, Denver, Colorado.
Denning, Scott, author, Society of Quality Assurance, publisher   +1 more
core   +1 more source

A Layered Governance Coverage Model for Decentralized Autonomous Organizations: Formalization, Empirical Analysis, and Implications for Blockchain-Based IoT/AI Systems

Information
Decentralized Autonomous Organizations (DAOs) enable blockchain-based collective governance, yet existing studies often evaluate DAO governance through isolated mechanisms, particularly voting systems.
Abeer S. Al-Humaimeedy, Rand Alkharashi
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Iterative Retrieval‑Augmented Generation Method for Aviation Standards Based on Large Language Models

Nanjing Hangkong Hangtian Daxue Xuebao
Aviation standards are characterized by complex data structures， rigorous semantics， and frequent cross‑document references， which pose significant challenges for achieving efficient and accurate knowledge acquisition and question‑answering applications.
QIN Xiaorui, HE Liu, AN Ran, ZENG Jianghui, LIU Shuyan, WANG Shaofeng, TIAN Yu   +6 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

A taxonomy of spatial data integrity constraints

, 1997
Spatial data quality has become an issue of increasing concern to researchers and practitioners in the field of Spatial Information Systems (SIS). Clearly the results of any spatial analysis are only as good as the data on which it is based.
Cockcroft, Sophie
core  

The ecosystem of ethics & support of big data research

, 2016
Presented at the National data integrity conference: data sharing: the how, why, when and when not to share held on June 2-3, 2016 at University of Colorado, Denver, Colorado.
Tijerina, Bonnie, author, Society of Quality Assurance, publisher   +1 more
core   +1 more source

EPOPTIS: A Monitoring-as-a-Service Platform for Internet-of-Things Applications

Sensors
The technology landscape has been dynamically reshaped by the rapid growth of the Internet of Things, introducing an era where everyday objects, equipped with smart sensors and connectivity, seamlessly interact to create intelligent ecosystems.
Petros Zervoudakis, Nikolaos Karamolegkos, Eleftheria Plevridi, Pavlos Charalampidis, Alexandros Fragkiadakis   +4 more
doaj   +1 more source