Results 41 to 50 of about 3,166,032 (228)

Inferential Statistics Is an Unfit Tool for Interpreting Data

Applied Sciences, 2022
Null hypothesis significance testing is a commonly used tool for making statistical inferences in empirical studies, but its use has always been controversial. In this manuscript, I argue that even more problematic is that significance testing, and other abstract statistical benchmarks, often are used as tools for interpreting study data.
openaire   +2 more sources

Scale-Free model for governing universe dynamics

, 2009
We investigate the effects of scale-free model on cosmology, providing, in this way, a statistical background in the framework of general relativity.
Baronchelli A. Catanzaro M. Pastor-Satorras R., Barris B. J. et al, C. Autieri, Caccioli F. Dall'Asta L., Caccioli F. Dell'Asta L., Capozziello S., Croft R. A. C., Dodelson S., G. Iannone, Knop R. A., Kowalski M., McDonald P., Montoya J. M. Solè R. V., Netterfield C. B., O. Luongo, Peebles P. J. E., Perlmutter S., Pope A. C., Riess A. G., Riess A. G. et al, Sahni V., Scala A., Spergel D. N., Spergel D. N., Stompor R., Szalay A. S., Tonry J. L., van Kampen N. G., Visser M., Visser M., Visser M. Cattoën C., Weinberg S.   +31 more
core   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Labor market data [PDF]

A guide to the use and interpretation of labor market data (employment, unemployment, and wages).
Roy H. Webb, William Whelpley
core  

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

Ambiguous model learning made unambiguous with 1/f priors

, 2004
What happens to the optimal interpretation of noisy data when there exists more than one equally plausible interpretation of the data? In a Bayesian model-learning framework the answer depends on the prior expectations of the dynamics of the model ...
Atwal, Gurinder Singh, Bialek, William
core  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Data exploration systems for databases [PDF]

Data exploration systems apply machine learning techniques, multivariate statistical methods, information theory, and database theory to databases to identify significant relationships among the data and summarize information. The result of applying data
Greene, Richard J., Hield, Christopher
core   +1 more source

Bell's inequalities I: An explanation for their experimental violation

, 2001
Derivations of two Bell's inequalities are given in a form appropriate to the interpretation of experimental data for explicit determination of all the correlations.
Aspect, Bell, Bell, Clauser, Eberhard, Louis Sica, Peres   +6 more
core   +1 more source